Lung Cancer

Lung Cancer: treatments, trials & survival

Lung cancer is the leading cause of cancer death in the US. Explore current treatment advances, immunotherapy breakthroughs, and available clinical trials.

New Cases (2024)
234,580
5-Yr Survival
25.4%
Annual Deaths
125,070
Trend
Decreasing
See active trials

About Lung Cancer

Lung cancer is the leading cause of cancer death in the US. Explore current treatment advances, immunotherapy breakthroughs, and available clinical trials.

According to the National Cancer Institute’s SEER database, an estimated 234,580 new cases of lung cancer will be diagnosed in the United States in 2024, with approximately 125,070 deaths. The overall 5-year relative survival rate is 25.4%.

Source: NCI SEER Data: 1975–2022

Treatment options

Current treatment approaches for lung cancer depend on the stage at diagnosis, tumor characteristics, and the patient’s overall health. The most common options include:

1
Surgery
2
Chemotherapy
3
Radiation Therapy
4
Targeted Therapy (EGFR, ALK)
5
Immunotherapy (PD-L1)
6
Photodynamic Therapy

Treatment recommendations should always be discussed with a qualified oncologist. The options listed above are based on current clinical guidelines and may vary case by case.

Stages

Staging describes the extent of cancer in the body and is crucial for planning the most appropriate treatment:

Stage I Stage II Stage IIIA Stage IIIB Stage IV

Known risk factors

Understanding risk factors can support prevention and early detection. Known risk factors for this cancer include:

Smoking
Secondhand smoke
Radon exposure
Asbestos
Air pollution
Family history

Not sure where to start?

A patient navigator familiar with lung cancer can help you understand your options and connect you with top US hospitals. Free & confidential.

Active clinical trials

Clinical trials offer access to cutting-edge treatments not yet widely available. The trials below are sourced in real time from ClinicalTrials.gov:

Frequently asked questions

The 5-year relative survival rate for lung cancer is 25.4%. Early-stage detection significantly improves outcomes, with localized lung cancer having a 63% five-year survival rate.
Recent breakthroughs include immunotherapy drugs (pembrolizumab, nivolumab), targeted therapies for EGFR/ALK mutations, and antibody-drug conjugates showing promising results in clinical trials.
Yes, approximately 10-20% of lung cancers occur in people who have never smoked. Risk factors include radon exposure, secondhand smoke, and genetic predisposition.
The US Preventive Services Task Force recommends annual low-dose CT screening for adults aged 50-80 with a 20 pack-year smoking history who currently smoke or quit within the past 15 years.
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